Sangamo Therapeutics Announces Updated Preliminary Phase 1/2 Data in Fabry Disease Clinical Study Showing Continued Tolerability and Sustained Elevated -gal A Enzyme Activity in Five Longest Treated Patients | Sangamo Therapeutics, Inc. Benefits are great. Favorable. Factors that could cause actual results to differ include, but are not limited to, risks and uncertainties related to the effects of the evolving COVID-19 pandemic and the impacts of the pandemic and other macroeconomic factors, including as a result of the ongoing conflict between Russia and Ukraine, on the global business environment, healthcare systems and business and operations of Sangamo and our collaborators, including the initiation and operation of clinical trials; the research and development process, including the enrollment, operation and results of clinical trials and the presentation of clinical data; the uncertain timing and unpredictable nature of clinical trial results, including the risk that therapeutic effects in the Phase 3 AFFINE trial will not be durable in patients as well as the risk that the therapeutic effects observed in the latest preliminary clinical data from the Phase 1/2 STAAR study and the Phase 1/2 PRECIZN-1 study will not be durable in patients and that final clinical trial data from the study will not validate the safety and efficacy of isaralgagene civaparvovec, or BIVV003 (formerly known as SAR44513); the unpredictable regulatory approval process for product candidates across multiple regulatory authorities, including the potential that health authorities will not issue the required protocol amendment approvals in the Phase 3 AFFINE trial in a timely manner, or at all; reliance on results of early clinical trials, which results are not necessarily predictive of future clinical trial results, including the results of any Phase 3 trial of our product candidates; our limited experience manufacturing biopharmaceutical products, including the risks that we may be unable to maintain compliant manufacturing facilities, build additional facilities and manufacture our product candidates as intended; the potential for technological developments that obviate technologies used by Sangamo; the potential that Sangamo will not be able to identify and secure options or new collaborators for the BIVV003 program; the potential for Sangamo to cease development of the BIVV003 program, whether due to its inability to secure options to advance the program or otherwise;our lack of resources to fully develop, obtain regulatory approval for and commercialize our product candidates; and our ability to achieve expected future financial performance. Now many are ending their programs. Due to the split at Richmond and Brisbane, there was confusion on which site to interview. Sangamo uses its deep scientific expertise and proprietary zinc finger technology to create genomic cures for patients suffering from severe diseases for which todays medicine can only offer symptom management at best. We completed the transition of Sanofis rights and obligations under the collaboration developing BIVV003, formerly known as. About a day or two. Louise Wilkieir@sangamo.com See 1 answer. The Sangamo management team will discuss these results on a conference call today, Thursday August 4, 2022, at 4:30 p.m. Eastern Time. The increase of $1.5 million in revenues was primarily attributed to an increase of $1.3 million in revenue related to our collaboration agreement with Novartis and an increase of $0.8 million in revenue related to our collaboration agreement with Sanofi. Patient dosing is expected to resume in October New York, NY, and Brisbane, California, September 22, 2022 - Pfizer and Sangamo Therapeutics announced that the Phase 3 AFFINE study evaluating giroctocogene fitelparvovec, an investigational gene therapy for patients with moderately severe to severe hemophilia A, has re-opened recruitment. Fabry disease Reported data updates from the Phase 1/2 STAAR studys dose escalation phase; Dose expansion phase underway and dosing commenced; Phase 3 planning progresses. On a GAAP basis, we continue to expect total operating expenses in the range of approximately $320 million to $350 million in 2022, which includes non-cash stock-based compensation expense. Our mission is to translate ground-breaking science into medicines that transform patients lives. Find your private company bowl on Fishbowl, join the hottest conversation with your colleagues anonymously. The link to access the live webcast can also be found on the Sangamo Therapeutics website in the Investors and Media section under Events and Presentations. Participants should register for, and access, the call using this link. Difficult. We expect to present updated data from the Phase 1/2 PRECIZN-1 study via a poster presentation at the 64th. To supplement our financial results and guidance presented in accordance with GAAP, we present non-GAAP total operating expenses, which exclude stock-based compensation expense from GAAP total operating expenses. We believe that this non-GAAP financial measure, when considered together with our financial information prepared in accordance with GAAP, can enhance investors and analysts ability to meaningfully compare our results from period to period and to our forward-looking guidance, and to identify operating trends in our business. Recruiter set up the interview. 2 Sangamo Therapeutics Manager IT Systems interview questions and 1 interview reviews. Good people, culture, benefits and great pipeline projects. Employees rate Sangamo Therapeutics 4.2 out of 5 stars based on 55 anonymous reviews on Glassdoor. General high turnover rate in biotech industry applies here as well. Total operating expenses on a GAAP basis for the second quarter ended June 30, 2022, were $75.1 million, compared to $76.6 million for the same period in 2021. Both sides asked questions and got the answers we need, and after the interview, I was even more excited to join the company. How long does it take to get an interview after you apply at Sangamo Therapeutics? Good overall compensation and benefits. The Sangamo management team will discuss these results on a conference call today, Thursday November 3, 2022, at 4:30 p.m. Eastern Time. Actual results may differ materially from those projected in these forward-looking statements due to the risks and uncertainties described above and other risks and uncertainties that exist in the operations and business environments of Sangamo and our collaborators. Gene editing is a very compelling concept for physicians. The Phase 1/2 STAAR study has transitioned into the expansion phase, with the first five expansion patients dosed at the 5e13 vg/kg dose level, including the first two female patients. The interview was timely, provided an overview of the company and of the role, asked the candidate to go over their relevant career trajectory and competences. As of the November 15, 2022, supplemental cutoff date, 13 patients exhibited supraphysiological levels of -Gal A activity, sustained for over two years for the patient with the longest follow-up. Sickle cell disease Completed transition of program back to Sangamo; advanced manufacturing activities in anticipation of dosing in Q3; Phase 3 planning progresses. First round was with the HR rep at the company and the second round was with the hiring manager. American Society of Gene and Cell Therapy (ASGCT) Profiled significant pre-clinical progress across Sangamos innovative pipeline and platform. Actual results may differ materially from those projected in these forward-looking statements due to the risks and uncertainties described above and other risks and uncertainties that exist in the operations and business environments of Sangamo and our collaborators. Our scientists are leaders in the. Company seemed to have an outdated and rigid mindset. I interviewed at Sangamo Therapeutics. Cash, cash equivalents and marketable securities as of September 30, 2022, were $350.3 million, compared to $464.7 million as of December 31, 2021. Our platforms have yielded multiple clinical stage programs that could provide value in the near-to-mid-term. We completed manufacturing of the dose for the second patient, who recently received a kidney transplant. Coworkers are all very helpful and friendly. These increases were partially offset by a decrease of $0.7 million in revenue related to our collaboration agreement with Biogen. Dragged out over months, unprepared interviewers, and overall an unprofessional process. Sangamo is one of the few companies pursuing programs across the spectrum of genomic medicine. Once registered, participants will be given the option to either dial into the call with the number and unique passcode provided or to use the dial-out option to connect their phone instantly. 89% of employees would recommend working at, According to anonymously submitted Glassdoor reviews, Sangamo Therapeutics employees rate their compensation and benefits as 4.0 out of 5. Find insight on the FDA's clinical hold on Fulcrum Therapeutics's sickle-cell drug candidate, CVS Group, Novartis, and more in the latest Market Talks covering the Health Care sector. A pivotal readout is expected in the first half of 2024. This rating has been stable over the past 12 months. Since we dosed the first patient in the Phase 1/2 STEADFAST study evaluating TX200, our wholly owned autologous CAR-Treg cell therapy treating patients receiving an HLA-A2 mismatched kidney from a living donor, the product candidate continues to be generally well tolerated, with no treatment related adverse events. HR screen is just going over the Job Description and why Sangamo. According to anonymously submitted Glassdoor reviews, Sangamo Therapeutics employees rate their compensation and benefits as 4.0 out of 5. Guided by Science. Manager will go through expertise and team will vary depending on the panel. Available materials will be found on the Sangamo Therapeutics website after the event. Sangamo Therapeutics is a genomic medicine company focused on leveraging our novel platforms and scientific expertise to advance clinical programs. We continue to expect non-GAAP total operating expenses, excluding estimated non-cash stock-based compensation expense of approximately $40 million, in the range of approximately $280 million to $310 million in 2022. I applied through a recruiter. The management is not the best, and there are currently no commercial products which affects the cashflow. Sangamo Therapeutics Inc (NASDAQ: SGMO) announced updated preliminary data as of October 20, 2022, the cutoff date from the Phase 1/2 STAAR study of isaralgagene civaparvovec, or ST-920, a wholly owned gene therapy product candidate for Fabry disease. The process took 3 months. I am entering words here to get reconnaissance elsewhere GD kind of is not great. 38% of job seekers rate their interview experience at Sangamo Therapeutics as positive. Once registered, participants will be given the option to either dial into the call with the number and unique passcode provided, or to use the dial-out option to connect their phone instantly. The process took 3 months. Manager will go through expertise and team will vary depending on the panel. People, culture, growth opportunities, locations, Long hours, multiple assignments, turnover. Participants should register for, and access, the call using this link. Analyst Report: Alnylam Pharmaceuticals, Inc. Analyst Report: BioMarin Pharmaceutical Inc. NasdaqGS - NasdaqGS Real Time Price. I interviewed at Sangamo Therapeutics in Jan 2021. Were pioneering the future of genomic medicine, Sangamo Therapeutics Reports Recent Business Highlights and Fourth Quarter and Full Year 2022 Financial Results, Sangamo Therapeutics Announces Evidence of Clinical Benefit in Phase 1/2 STAAR Study in Fabry Disease. Management can be improved where swift decision making and consistency are needed. Non-GAAP operating expenses, which exclude stock-based compensation expense, for the second quarter ended June 30, 2022, were $67.2 million, compared to $67.1 million for the same period in 2021. How many more words to count? Manufacturing of product candidates using improved methods progressed in the Phase 1/2 study. Duties of the advertised position and the involved project. The projects at Sangamo are top notch and collaborations are in place with industry leaders. These forward-looking statements include, without limitation, statements relating to: the therapeutic and commercial potential of our product candidates and their ability to generate value for our shareholders, the anticipated plans and timelines of Sangamo and our collaborators for screening, enrolling and dosing patients in and conducting our ongoing and potential future clinical trials and presenting clinical data from our clinical trials, including plans to dose patients in the expansion phase of, and the presentation of updated clinical data from, the Phase 1/2 STAAR study and updates regarding the PRECIZN-1 study, the dosing of patients with product candidates using improved manufacturing methods in the PRECIZN-1 study and the potential impacts thereof, as well as the timing and expectations for completion of dosing in such study, the expected timeline for dosing additional patients in the STEADFAST study, the anticipated advancement of our product candidates to late-stage development including potential future Phase 3 trials, plans and timing regarding the expected resumption of dosing of patients in the Phase 3 AFFINE trial and the presentation of data from such trial, our 2022 financial guidance related to GAAP and non-GAAP total operating expenses and stock-based compensation, and other statements that are not historical fact. These statements are not guarantees of future performance and are subject to certain risks and uncertainties that are difficult to predict. All five patients who began the dose escalation pha. - Achieved 78% globotriaosylceramide (Gb3) substrate clearance at 6-months and 77% reduction in urine podocyte loss in one of, BRISBANE, Calif. --(BUSINESS WIRE)--Feb. 21, 2023-- Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, announced today that the company is scheduled to hold a conference call on Wednesday, February 22, 2023 at 4:30 p.m. Glassdoor users rated their interview experience at. Dosing of this second patient is expected later in the third quarter of 2022. No post about Sangamo Therapeutics, Inc. yet, Hemophilia Market to Showcase Robust Growth in the Upcoming Year to 2032 | MobileODT, Gals Bio Ltd, DiagnoseSt, Global mRNA Vaccine Market Size And Forecast | Argos Therapeutics BioNTech AG, CureVac AG, eTheRNA Immunotherapies, Ethris GmbH, Incellart, Moderna Sangamo Therapeutics Tiba Biotech, Translate Bio, Inc. Sioux City Catholic Globe, We don't have enough salaries for Working in the company was very fun, I learned a lot about the technology that the company uses and about the different methodologies and techniques Sangamo has. I interviewed at Sangamo Therapeutics. February 27, 2023 9:47 am. Find a Great First Job to Jumpstart Your Career, Getting a Job Is Tough; This Guide Makes it Easier, Climb the Ladder With These Proven Promotion Tips, A Guide to Negotiating the Salary You Deserve. It was then followed by individual interviews with different members of the team, To get a job at Sangamo Therapeutics, browse, Overall, 89% of employees would recommend, Work Here? However, after the last interview I haven't heard back from them. We have raised approximately $75.1 million in net proceeds under our at-the-market offering program from January 1, 2022 through October 31, 2022. To supplement our financial results and guidance presented in accordance with GAAP, we present non-GAAP total operating expenses, which exclude stock-based compensation expense from GAAP total operating expenses. Why Sangamo? Sangamo Therapeutics Reports Recent Business Highlights and Third Quarter 2022 Financial Results News Release Sangamo Therapeutics Announces Updated Preliminary Phase 1/2 Data in Fabry Disease Showing Continued Tolerability and Sustained Elevated -Gal A Enzyme Activity in Nine Patients News Release Free interview details posted anonymously by Sangamo Therapeutics interview candidates. Currency in USD, Gain actionable insight from technical analysis on financial instruments, to help optimize your trading strategies. How many more words to count? A pivotal data readout is estimated in late 2023 or early 2024. Company is very dedicated to patient engagement as well as inclusion and diversity.Read More. Be the first to find this interview helpful. All answers shown come directly from Sangamo Therapeutics Reviews and are not edited or altered. Hemophilia A Pfizer advised us that it continues to expect resumption of dosing in Q3 2022; pivotal data read-out expected in late 2023 or early 2024. Was told I was a candidate in the running but they never got back to me and never responded to multiple calls or emails, Anonymous Interview Candidate in San Francisco, CA, I applied online. The decrease of $2.1 million in revenues was primarily attributable to a decrease of $1.9 million and $1.6 million related to our collaboration agreements with Novartis and Biogen respectively, and a decrease of $1.1 million due to the termination of our collaboration agreement with Sanofi. Management is very accessible. Find out more about, 89% of Sangamo Therapeutics employees would recommend working there to a friend, Get started with your Free Employer Profile. https://www.openpr.com/news/2771399/hemophilia-market-to-showcase-robust-growth-in-the-upcoming-year, https://www.catholicglobe.org/global-mrna-vaccine-market-insight-size-and-forecast/. Candidates give an average difficulty score of 2.8 out of 5 (where 5 is the highest level of difficulty) for their job interview at Sangamo Therapeutics. HR screen is just going over the Job Description and why Sangamo. BRISBANE, Calif.--(BUSINESS WIRE)--Aug. 4, 2022-- A total of 16 study sites are now open and recruiting, including the first sites in, We plan to provide updated results from the STAAR study in the second half of 2022, including at the. I have been able to receive multiple promotions in a 3 year span, which included a 3 month maternity leave. Brisbane, California, November 16, 2022 Dosing has resumed in the Phase 3 AFFINE study evaluating giroctocogene fitelparvovec, an investigational gene therapy for patients with moderately severe to severe hemophilia A. Dosing resumed on November 10, 2022. Dosed the second patient in the Phase 1/2 STEADFAST study evaluating TX200, our wholly owned autologous CAR-Treg cell therapy treating patients receiving an HLA-A2 mismatched kidney from a living donor. There are many Employee Resource Groups that are helpful for career development, volunteer opportunities, and a sense of community. However, I never hear back from them since then. Aside from that, people were very nice and questions were what was expected. Interview experience. Sangamo Therapeutics has an overall rating of 4.2 out of 5, based on over 55 reviews left anonymously by employees. Changes wont be saved until you sign up for an Enhanced Profile subscription. Nothing striking about this particular process. Key Insights Institutions' substantial holdings in Sangamo Therapeutics implies that they have significant influence Gene therapy offered hope for thousands of sickle cell disease patients. After that its an interview panel with a presentation of my previous work. The hiring process at Sangamo Therapeutics takes an average of 31 days when considering 17 user submitted interviews across all job titles. Tell me a little about your self. There can be no assurance that we and our collaborators will be able to develop commercially viable products. Candidates applying for Contractor had the quickest hiring process (on average 1 day), whereas Project Manager roles had the slowest hiring process (on average 120 days). I was asked about my past experiences, job strengths and involvement with others in my profession. I interviewed at Sangamo Therapeutics (New York, NY). We are passionate about our science and driven by the purpose it serves. My three times follow-up with two different HR reps was left unanswered. Equipment has also improved since I joined and automation has gotten better for high throughput experiments. Subscribe to Yahoo Finance Plus to view Fair Value for SGMO. Conference Call to Discuss Third Quarter 2022 Results. Super friendly working environment and very nice people. Total operating expenses on a GAAP basis for the third quarter ended September 30, 2022 were $81.3 million, compared to $77.0 million for the same period in 2021. "This has been a year marked by progress across our pipeline. Would never interview here again, HR screen, Manager, Team. Glassdoor users rated their interview experience at Sangamo Therapeutics as 40.0% positive with a difficulty rating score of 2.86 out of 5 (where 5 is the highest level of difficulty). Preliminary data showed all nine patients from the dose escalation phase exhibited sustained elevated -Gal A activity, ranging from nearly 2-fold to 30-fold of mean normal, for up to 23 months post dosing, as of the last date of measurement. Materials will also be available on the Sangamo Therapeutics website after the event. Nothing striking about this particular process. Super friendly working environment and very nice people. Morale was specifically low and retention was really bad at the company when I left in Dec 2021 as management had become quite manipulative trying to find any reasons not to give people raises. I interviewed at Sangamo Therapeutics in Jan 2021. What are perks and other benefits like at Sangamo Therapeutics? Sangamo Therapeutics is a clinical-stage biopharmaceutical company with a robust genomic medicines pipeline. Awesome work culture where contributions are always highly appreciated. Sangamo plans to participate in the following events in the fourth quarter: Access links for available webcasts for these investor conferences will be available on the Sangamo Therapeutics website in the Investors and Media section under Events and Presentations. Some details of my previous projects. Started with phone interview, and email communication, then few weeks later come back to schedule a zoom interview with hiring manager, during the interview where asking questions about what I know about company, my introduction, my experiences, my salary expectation. Duties of the advertised position and the involved project. This is based on 44 anonymously submitted reviews on Glassdoor. Sickle cell disease Dosed sixth patient, the second with a product candidate manufactured using improved methods; Phase 3 planning progresses. Revenues for the third quarter ended September 30, 2022 were $26.5 million, compared to $28.6 million for the same period in 2021. Cash, cash equivalents and marketable securities as of June 30, 2022, were $363.7 million, compared to $464.7 million as of December 31, 2021. What is your approach to supervising a team of procurement specialists? As we look to next year and beyond, I am confident in Sangamos ability to carry out our mission of developing transformational therapies for patients in need.. The process took 3 days. Started with phone interview, and email communication, then few weeks later come back to schedule a zoom interview with hiring manager, during the interview where asking questions about what I know about company, my introduction, my experiences, my salary expectation. Common stages of the interview process at Sangamo Therapeutics according to 17 Glassdoor interviews include: Find a Great First Job to Jumpstart Your Career, Stand Out From the Crowd With the Perfect Cover Letter, How to Prepare for Your Interview and Land the Job. Management is very accessible. I applied online. The process took 4 weeks. Pays significantly less than South San Francisco companies. (unaudited; in thousands, except per share data), View source version on businesswire.com: https://www.businesswire.com/news/home/20221103005505/en/, Investor Relations & Media Inquiries Do the numbers hold clues to what lies ahead for the stock? Conference Call and Webcast Scheduled for 4:30 p.m. Eastern Time. What is the interview process like at Sangamo Therapeutics? Pfizer and Sangamo announced that recruitment has re-opened in the Phase 3 AFFINE trial of giroctocogene fitelparvovec, an investigational gene therapy we are developing with Pfizer for patients with moderately severe to severe hemophilia A. The process took 4 weeks. In the third quarter, we continued to advance our clinical trials and preclinical activities while maintaining fiscal discipline and operational excellence, said Sandy Macrae, Chief Executive Officer of Sangamo. Sangamo is a genomic medicine company that seeks to help millions of people who suffer from severe diseases for which today's medicine can only offer symptom management at best. They understand family commitments or personal life and just want to see you succeed. The process took 4 weeks. In June, the Safety Monitoring Committee endorsed progressing the Phase 1/2 STAAR study evaluating isaralgagene civaparvovec, our wholly owned gene therapy product candidate for the treatment of Fabry disease, from the dose escalation phase into the expansion phase at the dose level of 5e13 vg/kg. Barclays Gene Editing & Gene Therapy Summit. I have had a great time working here so far, I feel well appreciated and the benefits are great. There can be no assurance that we and our collaborators will be able to develop commercially viable products. For Sangamo Therapeutics, science is a means to develop new medicines with the potential to transform the lives of patients living with serious genetic diseases. Working in the company was very fun, I learned a lot about the technology that the company uses and about the different methodologies and techniques Sangamo has. Sangamo was founded in 1995 as Sangamo BioSciences, Inc. in order to research new technologies for genome editing. 89% of employees would recommend working at Sangamo Therapeutics to a friend and 75% have a positive outlook for the business. Cash, cash equivalents and marketable securities. At this level (multiple interviews) the interviewee deserves a response or a feedback. Forward-looking statements contained in this announcement are made as of this date, and we undertake no duty to update such information except as required under applicable law. Sangamo is a genomic medicine company that seeks to help millions of people who suffer from severe diseases for which todays medicine can only offer symptom management at best. Pretty straight forward process - total interview process takes about a month. Based on 2 interviews. Our rare disease clinical programs are feeding insights across our portfolio and paving the way for research and preclinical programs across larger patient populations. We have a robust preclinical pipeline with programs in emerging areas that could provide value in the mid-to-long term. Our platforms have yielded multiple clinical stage programs that could provide value in the near-to-mid-term. Reviews 5.0 1 reviews 5.0 Career Growth 5.0 Work - Life Balance 4.0 Compensation / Benefits 5.0 Company Culture 4.0 Management POPULAR 4.0 "Great overall biotech company" I interviewed at Sangamo Therapeutics in Jul 2021. Candidates give an average difficulty score of 2.8 out of 5 (where 5 is the highest level of difficulty) for their job interview at Sangamo Therapeutics. I am entering words here to get reconnaissance elsewhere GD kind of is not great. Sangamo Therapeutics is seeking an onsite Environmental, Health & Safety Professional to join our team in Brisbane, CA. We're pioneering the future of genomic medicine It was then followed by individual interviews with different members of the team, Terrible interview process- the worst Ive ever had. I interviewed at Sangamo Therapeutics in Aug 2020, Nice set of interviews and great questions. To learn more, visit www.sangamo.com and connect with us on LinkedIn and Twitter. Glassdoor has millions of jobs plus salary information, company reviews, and interview questions from people on the inside making it easy to find a job thats right for you. While not required, it is recommended you join 10 minutes prior to the event start. 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